Pharmacogenetic (PGx) Test Details
Blue Ridge Laboratories’ 44 gene Pharmacogenetic (PGx) test determines how a patient metabolizes all classes of medications to help guide most effective treatment options for most medical conditions while reducing the risk of trial and error prescribing as well as reducing adverse drug reactions. Additionally, this panel can aid with dosing adjustments based on an individuals efficacy at isolated medication metabolism. Blue Ridge Laboratories provides the most comprehensive pharmacogenetic panel in the industry which includes genes associated with drug metabolism with high level evidence and clinically actionable guidelines, as well as, genes with PharmGKB evidence of 2 or higher. Our “Sample Test Results” give providers a glimpse into a sample test result that is run for every patient.
Preferred Specimen
Buccal Swab
Turn-around Time
Approximately 10 – 14 days
Download Pharmacogenetics Flyer
Requisition Forms
Doctor & Patient
Use this form if you have both the Provider and Patient information.
Doctor Only
Use this form if you don’t have or cannot provide the Patient’s contact information.
Record Release Form
Consent to the release of records.
Gene Selection
| ABCB1 | ACE | ANKK1 | APOE | ATM | BCHE | CES1 | COMT |
| CYP2B6 | CYP2C19 | CYP2C8 | CYP2C9 | CYP2D6 | CYP3A4 | CYP3A5 | CYP4F2 |
| DPYD | DRD2 | ERCC1 | F2 | F5 | G6PD | GGCX | GRIK4 |
| GSTP1 | HLA-B | HTR1A | HTR2A | HTR2C | IFNL4 | ITPA | KIF6 |
| MTHFR | NAT2 | NQ01 | NUDT15 | OPRM1 | RYR1 | SLCO1B1 | TPMT |
| UGT1A1 | UGT1A4 | VKORC1 | XRCC1 |
Panel Description
Overview:
Blue Ridge Laboratories’ Pharmacogenetic (PGx) tests gives clinicians the tools to better understand how their patients will respond to certain medications.
With PGx testing, it’s possible to tailor medication plans to a patient’s specific genetic makeup. This can lead to reduced medical costs for patients and providers, safer medication plans, and more efficient drug efficacy. The PGx Comprehensive Panel includes genes associated with drug metabolism with high level evidence and clinically actionable guidelines, in addition to genes with PharmGKB evidence of 2 or higher.
What can testing tell us?
PGx testing can reveal if a person is a fast, normal, or slow metabolizer. A person’s metabolism changes the way their body responds to medication, including:
• Toxicity
Excessive amounts of the drug accumulate in the bloodstream, resulting in ADRs.
• Lack of Efficacy
The bloodstream cannot absorb enough of the drug to achieve a therapeutic effect.
• Hypersensitivity
Normal amounts of the drug enter the bloodstream, but even this is enough to trigger severe reactions in people with hypersensitivity to the medication.
What are the potential benefits for my patient?
Identify which drug may be most effective before treatment starts
PGx testing can help clinicians choose the most effective drug for each patient, minimize the risk of adverse reactions, and reduce hospitalizations.
Reduce the risk of adverse events related to certain drugs
PGx testing can assess a patient’s risk for adverse drug reactions before they take the medication which can improve patient safety and minimize costs for healthcare facilities.
Adjust and optimize the dose of current medications
PGx testing can help clinicians predict the appropriate dose of medication for their patient. This allows them to create more personalized medication plans to maximize efficacy and
reduce pharmacy costs.
Improved Patient Care
PGx test results become part of a patient’s medical record, allowing physicians to make more informed decisions when prescribing medications for future medical issues.
Pharmacogenetic (PGx) Test FT-TP01241
PGx is the study of how your genes may affect your body’s response to, and interaction with, some prescription or over-the-counter medications. The PGx test analyzes a patient’s genetic make-up to optimize drug selection and dosing
Frequently Asked Questions
How much does it cost?
Blue Ridge Laboratories accepts all major insurance, Medicare, and Medicaid. We believe that healthcare should be accessible to all patients. We have created special access programs to cover unforeseen co-payments and uninsured patients. Please contact us for any billing questions.
How do you bill insurance?
Blue Ridge Laboratories will collect the patient’s insurance information and submit for the patient. Blue Ridge Laboratories handles preauthorizations as well.
Who has to order the testing?
The order (requisition) forms will be completed by the referring physician, physician assistant, or nurse practitioner. Blue Ridge Laboratories offers cash pay options for tests that do not require insurance.
Where can I get the testing?
Patents can request test kits online by clicking the link to GET MY TEST or request from their medical provider.
How long does it take to get results?
Result times vary but for the majority of the testing we offer, turnaround times are between 14 and 21 days.
Who will talk with me about the test results?
Blue Ridge Laboratories partners with genetic counselors, who are available to help interpret results and answer questions for patients or providers.
Can my family be tested?
If you have a hereditary disorder with an identified genetic variant, your family can obtain genetic testing through their physician, physician assistant, or nurse practitioner.
Can I get more than one test?
Yes, we have plenty of patients who meet medical necessity requirements for multiple panels. However, each test requires an individual buccal (cheek) swab and requisition form signed by the patient and the provider.