Cardiac Test Details
The Comprehensive Cardiovascular Panel examines 117 genes associated with hereditary cardiomyopathies and arrhythmias.
Individuals often have clinical overlap between inherited arrhythmias and cardiomyopathies. The benefit of comprehensive cardiovascular testing includes confirming a diagnosis to determine risks and assist with individualized management based on cardiovascular guidelines. Patients with a family history of a pathogenic variant may benefit from a genotypic diagnosis in order to direct future screening and management.
Preferred Specimen
Buccal Swab
Turn-around Time
Approximately 14 – 21 days
Requisition Forms
Doctor & Patient
Use this form if you have both the Provider and Patient information.
Doctor Only
Use this form if you don’t have or cannot provide the Patient’s contact information.
Record Release Form
Consent to the release of records.
Gene Selection
| ABCC9 | ACTA2 | ACTC1 | ACTN2 | ACVRL1 | AGL | AKAP9 | ALMS1 |
| ANK2 | APOB | BAG3 | BMPR2 | CACNA1C | CACNA1S | CACNB2 | CALM1 |
| CALM2 | CALM3 | CASQ2 | CAV1 | CAV3 | COL3A1 | CRYAB | CSRP3 |
| DES | DMD | DOLK | DSC2 | DSG2 | DSP | EMD | ENG |
| EYA4 | F9 | FBN1 | FHL1 | FKRP | FKTN | FLNC | GAA |
| GATAD1 | GDF2 | GLA | GPD1L | HCN4 | JPH2 | JUP | KCNA5 |
| KCND3 | KCNE1 | KCNE2 | KCNE3 | KCNH2 | KCNJ2 | KCNJ5 | KCNQ1 |
| LAMA4 | LAMP2 | LDB3 | LDB3 | LDLR | LDLRAP1 | LMNA | MYBPC3 |
| MYH11 | MYH6 | MYH7 | MYL2 | MYL3 | MYLK | MYOZ2 | MYPN |
| NEXN | NKX2-5 | PCSK9 | PKP2 | PLN | PRKAG2 | PRKG1 | PROC |
| PROS1 | PTPN11 | RAF1 | RBM20 | RIT1 | RYR1 | RYR2 | SCN10A |
| SCN1B | SCN2B | SCN3B | SCN4B | SCN5A | SERPINC1 | SGCD | SLC22A5 |
| SMAD3 | SMAD4 | SNTA1 | SOS1 | TAZ | TBX20 | TBX5 | TCAP |
| TGFB2 | TGFB3 | TGFBR1 | TGFBR2 | TMEM43 | TNNC1 | TNNI3 | TNNT2 |
| TPM1 | TRDN | TRPM4 | TTN | TTR | VCL |
Disorders Tested
- Alstrom syndrome
- Andersen-Tawil syndrome
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Atrial fibrillation
- Barth syndrome
- Brugada syndrome
- Cantu syndrome
- Carnitine palmitoyltransferase II deficiency
- Carvajal syndrome
- Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
- Combined oxidative phosphorylation deficiency (COXPD)
- Congenital disorder of glycosylation DOLK-CDG (CDG-Im)
- Danon disease
- Dilated cardiomyopathy
- Dystrophinopathy
- Dystrophy-dystroglycanopathy types A4, B4, C4, A5, B5 and C5
- Emery-Dreifuss muscular dystrophy (EDMD)
- Fabry disease
- Glycogen storage disease
- type II (Pompe disease) and type III
- Hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis)
- Hypertrophic cardiomyopathy (HCM/HOCM)
- Inherited cardiomyopathies
- Jervell and Lange-Nielson syndrome (JLNS)
- Left ventricular noncompaction
- Limb-girdle muscular dystrophy type 2F
- Long QT syndrome (LQTS)
- Naxos disease
- Noonan-spectrum disorders
- Primary carnitine deficiency
- Propionic acidemia
- Restrictive cardiomyopathy (RCM)
- SDHA-related mitochondrial complex II deficiency
- Short QT syndrome (SQTS)
- Timothy syndrome
- Very long chain acyl-CoA dehydrogenase (VLCAD) deficiency
- Wolff-Parkinson-White syndrome (WPW)
Genetic Heart Health Screening
If you’re already seeing a cardiologist for heart problems, genetic testing might be ordered to find out more about your condition or rule out the causes of the disease. Cardiac Genetic testing can help refine your diagnosis and guide your treatment.
Inherited heart conditions include Cardiomyopathies and Arrhythmias. Most common heart condition symptoms are high blood pressure, high cholesterol, heart failure, aneurysms, fainting with exercise or emotional stress and irregular heartbeats.
Frequently Asked Questions
How much does it cost?
Blue Ridge Laboratories accepts all major insurance, Medicare, and Medicaid. We believe that healthcare should be accessible to all patients. We have created special access programs to cover unforeseen co-payments and uninsured patients. Please contact us for any billing questions.
How do you bill insurance?
Blue Ridge Laboratories will collect the patient’s insurance information and submit for the patient.
Who has to order the testing?
The order (requisition) forms will be completed by the referring physician, physician assistant, or nurse practitioner.
Where can I get the testing?
Patents can request test kits online by clicking the link to GET MY TEST or request from their medical provider.
How long does it take to get results?
Result times vary but for the majority of the testing we offer, turnaround times are between 14 and 21 days.
Who will talk with me about the test results?
Blue Ridge Laboratories has genetic counselors available to help interpret results and answer questions for patients or providers.
Can my family be tested?
If you have a hereditary disorder with an identified genetic variant, your family can obtain genetic testing through their physician, physician assistant, or nurse practitioner.
Can I get more than one test?
Yes, we have plenty of patients who meet medical necessity requirements for multiple panels. However, each test requires an individual buccal (cheek) swab and requisition form signed by the patient and the provider.